Knoxville and Myrtle Beach are 6 hours 42 mins far apart, if you drive non-stop . This is the fastest route from Knoxville, TN to Myrtle Beach, SC. The halfway point is Joanna, SC. Knoxville, TN and Myrtle Beach, SC are in the same time zone (EDT). Current time in both locations is 10:39 pm.

Find the best roads to take from Knoxville to Myrtle Beach by car if you're planning a trip. If you want to explore small towns along the way, get a list of cities between Knoxville, TN and Myrtle Beach, SC. Looking for alternate routes? Explore all of …

Driving directions from Knoxville, Tennessee 37902, US, Knoxville, Tennessee to Myrtle Beach, South Carolina 29577, US, Myrtle Beach, South Carolina including road conditions, live traffic updates, and reviews of local businesses along the way.

The total driving distance from Knoxville, TN to Myrtle Beach, SC is 411 miles or 661 kilometers. Your trip begins in Knoxville, Tennessee. It ends in Myrtle Beach, South Carolina.

The cheapest way to get from Knoxville to Myrtle Beach costs only $90, and the quickest way takes just 3¾ hours. Find the travel option that best suits you.

How long is the drive from Knoxville, TN to Myrtle Beach, SC? The total driving time is 6 hours, 28 minutes. Your trip begins in Knoxville, Tennessee. It ends in Myrtle Beach, South Carolina. If you're planning a road trip, you might be interested in seeing the total driving distance from Knoxville, TN to Myrtle Beach, SC.

Get the driving directions and route from Knoxville, Tennessee to Myrtle Beach, South Carolina via I-40 and US-74.

The total driving distance from Knoxville, TN to Myrtle Beach, SC is 411 miles or 661 kilometers. The total straight line flight distance from Knoxville, TN to Myrtle Beach, SC is 326 miles . This is equivalent to 525 kilometers or 283 nautical miles .

Find the best roads to take from Myrtle Beach to Knoxville by car if you're planning a trip. If you want to explore small towns along the way, get a list of cities between Myrtle Beach, SC and Knoxville, TN. Looking for alternate routes? Explore all of …

Here's a sample itinerary for a drive from Knoxville to Myrtle Beach. If you're planning a road trip to Myrtle Beach, you can research locations to stop along the way. Make sure you check road conditions to double check the weather.