The EMBO Journal7d
PDE12 mediated pruning of the poly-A tail of mitochondrial DNA-encoded tRNAs is essential for survival
Mitochondrial DNA (mtDNA)-encoded RNA molecules undergo extensive processing to generate mature RNA, including removal of ...
The EMBO Journal2d
New players and targets in mannose 6-phosphate-dependent lysosomal sorting
Amidst the wide variety of glycan modifications that are carried out in the Golgi apparatus, the addition of mannose 6-phosphate (M6P) to the N-linked glycans of lysosome-resident hydrolase enzymes ...
The EMBO Journal7d
Soul Men and Women—what must science do to regain public trust?
Whether it amounts to anything in the very long run, preserving this planet and its occupants safely for the next hundred ...
The EMBO Journal12h
The N-terminal region of DNMT3A engages the nucleosome surface to aid chromatin recruitment
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. DNA methyltransferase 3A (DNMT3A) plays a ...
The EMBO Journal6d
Interleukin-2-mediated NF-κB-dependent mRNA splicing modulates interferon gamma protein production
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. IL-2 stimulation post-transcriptionally ...
The EMBO Journal6d
The DNA demethylase TET1 modifies the impact of maternal folic acid status on embryonic brain development
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Interactions between modified maternal folic ...
The EMBO Journal10d
Novel integrated multiomics analysis reveals a key role for integrin beta-like 1 in wound scarring
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. A high-resolution spatial multiomics approach ...
The EMBO Journal6d
STING induces HOIP-mediated synthesis of M1 ubiquitin chains to stimulate NF-κB signaling
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. STING activation by cyclic dinucleotides ...
The EMBO Journal8d
Viral N protein hijacks deaminase-containing RNA granules to enhance SARS-CoV-2 mutagenesis
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Host cell-encoded deaminases act as antiviral ...
The EMBO Journal2d
Melanin-like nanoparticles slow cyst growth in ADPKD by dual inhibition of oxidative stress and CREB
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Melanin-like nanoparticles (MNPs) have ...
The EMBO Journal8d
Sex-specific regulatory architecture of pancreatic islets from subjects with and without type 2 diabetes
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Patients with type 2 and type 1 diabetes (T2D ...