Plants produce a wide diversity of compounds. Broadly, these are separated into primary metabolites, which are necessary for ...

Spatial metabolomics is transforming our understanding of microbial systems by uncovering the localized molecular dynamics ...

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Single cells are typically typed by clustering into discrete locations in reduced dimensional transcriptome space. Here we introduce Stator, a data-driven method that identifies cell (sub)types and ...

Plants that germinate in subterranean darkness grow heterotrophically from seed reserves. Under these conditions, hypocotyls elongate rapidly to reach the soil surface and ensure survival, while the ...

Using a zebrafish xenograft model, we visualized BC cells migrating along cerebral veins in real time, confirming an extravascular pathway to the brain. We identified LRP8, a receptor upregulated in ...

The DNA damage response (DDR) plays an important role in maintaining genome stability (Jeggo et al, 2016). This is particularly apparent in cancer, where cells hijack DDR by upregulation of the key ...

The accumulation of mitochondrial precursor proteins in the cytosol due to mitochondrial dysfunction compromises cellular proteostasis and is a hallmark of diseases. Why non-imported precursors are ...