Christian McCaffrey's injury against the Bills could be due to the heavy workload he received since returning to the 49ers.

49ers head coach Kyle Shanahan told reporters Monday that McCaffrey suffered a posterior cruciate ligament (PCL) injury ...

The 49ers have lost three games in a row, but their season isn't dead yet. Sure, they're in last place in the NFC West, but ...

The 2024 season has been a renaissance for running backs. After years of toiling away on middling teams, Philadelphia Eagles ...

The San Francisco 49ers' brutal battle against the injury bug continues to get worse, as they have lost their two main running backs — Christian ...

The 49ers signed two running backs to their practice squad after Christian McCaffrey and Jordan Mason were placed on injured ...

The San Francisco 49ers have signed a former New York Jets running back to replace the injured Christian McCaffrey and Jordan ...

The San Francisco 49ers placed running back Christian McCaffrey on injured reserve Tuesday a day after coach Kyle Shanahan ...

The San Francisco 49ers on Tuesday announced how they’d replace running back Christian McCaffrey. In a slew of roster moves ...

The San Francisco 49ers claimed running back Israel Abanikanda off waivers from the New York Jets on Tuesday, one day after ...

The San Francisco 49ers have officially placed running back Christian McCaffrey on injured reserve. He sustained a PCL injury ...

Isaac Guerendo and Will Levis are among UPI senior sports writer Alex Butler's top fantasy football waiver wire priorities ...