The Buffalo Bills' defense could receive a big boost for Sunday's night showdown against the San Francisco 49ers.

Buffalo Bills linebacker Matt Milano (58) reacts after a defensive play against the New York Jets during the first quarter of ...

The #Bills have activated Pro Bowl LB Matt Milano off Injured Reserve and he’ll play on Sunday against the #49ers for the ...

Here's what uniforms the Buffalo Bills and San Francisco 49ers will wear during their Week 13 matchup at Highmark Stadium: ...

The Buffalo Bills have activated Matt Milano from injured reserve, putting the starting linebacker in position to play Sunday ...

Three things I’m pondering as the Bills return from their bye for the stretch run… Mila-No More Waiting Matt Milano is ...

The National Weather Service has extended its "lake effect snow warning" in Buffalo through Monday at 7 p.m. ET, with ...

The Buffalo Bills are asking for snow shovelers to help shovel out Highmark Stadium in anticipation of the winter weather in ...

The National Weather Service has extended its "lake effect snow warning" in Buffalo through Monday at 7 p.m. ET, with ...

Ten months after their wild-card playoff game against the Pittsburgh Steelers was postponed due to blizzard conditions, the ...

The Buffalo Bills have reactivated All-Pro linebacker Matt Milano ahead of their Week 13 match up against the San Francisco ...

The Bills are activating Matt Milano (biceps) off injured reserve and the linebacker will make his long-awaited return on ...