Buffalo Bills quarterback Josh Allen and coach Sean McDermott reacted to forecasts of a snow game against the San Francisco ...

The Bills attempt to win seven in a row when they host the 49ers in this Week 13 NFL odds, prediction, and pick.

The Buffalo Bills will play the San Francisco 49ers at home at Highmark Stadium on “Sunday Night Football” in Week 13. The ...

WR Curtis Samuel (vs. 49ers) — Samuel made mincemeat out of the Chiefs in his last game. But with Keon Coleman and Dalton ...

How much weight do you want to put on the frozen-Fish angle? The forecast at Lambeau is 21 degrees, a real feel of 4 with 15 ...

The NFL star Buffalo Bills quarterback is a 6-foot-5 mountain of a man. For two kids given a dream come true, one of them adorably had no clue it was him.

Simpson carried the ball 29 times against the Lions and set a new NFL record with 273 rushing yards, breaking his own record ...

Daniel Jones reportedly signs with the Vikings. Saquon Barkley enters the MVP conversation, but Lamar Jackson’s case remains ...

San Francisco 49ers defensive end Nick Bosa missed Wednesday's practice as the team began preparations for Sunday's game ...

Bills' QB Josh Allen is the current favorite for MVP. Expectations aren't something I like to make a habit. However, it's ...

The Bills and 49ers meet on Sunday Night Football in a game with playoff implications for both teams. Here are three ...

While the 49ers look like an easy opponent, San Francisco's health could be a major factor in the game, warns one NFL expert.