SCY-247 inhibits glucan synthase, an enzyme involved in the formation of 1,3-beta-D-glucan, an essential component of the ...

The following is a summary of “Rezafungin versus caspofungin for patients with candidaemia or invasive candidiasis in the ...

PARSIPPANY, N.J.--(BUSINESS WIRE)--Melinta Therapeutics, LLC (Melinta), a commercial-stage company providing innovative therapies for acute and life-threatening illnesses, announced today, ten ...

Results: All positive blood cultures cleared between 3 and 7 days after initiation of caspofungin, the atrial vegetation resolved and the renal Candida bezoars disappeared. Renal and hepatic ...

Stone and colleagues [26] studied the pharmacokinetics of caspofungin acetate in 12 healthy male subjects involved in three Phase I trials. In the first dose-ranging study, subjects were given ...