The EMBO Journal1d
Glutamine sensing licenses cholesterol synthesis
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The mevalonate pathway produces essential ...
The EMBO Journal1d
Hair follicle stem cells and the collapse of self-tolerance in alopecia: the interplay of barrier function, the microbiome, and immunity
The hair follicle is thought to be a site of ‘immune privilege,’ or relative protection from autoimmune and inflammatory responses. In particular, the long-lived, quiescent hair follicle stem cells ...
The EMBO Journal2d
PARP1 condensates differentially partition DNA repair proteins and enhance DNA ligation
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Poly(ADP-ribose) polymerase 1 (PARP1) is one ...
The EMBO Journal3d
Leishmania protein KMP-11 modulates cholesterol transport and membrane fluidity to facilitate host cell invasion
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The first step of successful infection by any ...
The EMBO Journal4d
Histone modifications and Sp1 promote GPR160 expression in bone cancer pain within rodent models
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Increased H3K27ac levels upon tumor ...
The EMBO Journal4d
The USP12/46 deubiquitinases protect integrins from ESCRT-mediated lysosomal degradation
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The functions of integrins are tightly ...
The EMBO Journal4d
Making contact away from home: a bacterial secreted effector mediates inter-organelle communication
Inter-organelle communication via the formation of membrane contact sites (MCS) is essential for cell homeostasis. Bacterial pathogens residing in membrane bound vacuoles have exploited this ...
The EMBO Journal5d
Identifying T-cell clubs by embracing the local harmony between TCR and gene expressions
TCRclub integrates scRNA-seq and scTCR-seq data by local harmony to identify functionally similar T cell groups, termed ...
The EMBO Journal5d
Rett syndrome: interferon-γ to the rescue?
In conclusion, this intriguing report builds on the work of many other groups by further unraveling MECP2 function in the ...
The EMBO Journal5d
The L27 domain of MPP7 enhances TAZ-YY1 cooperation to renew muscle stem cells
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Stem cells regenerate differentiated cells to ...
The EMBO Journal6d
Rab2A-mediated Golgi-lipid droplet interactions support very-low-density lipoprotein secretion in hepatocytes
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Lipid droplets (LDs) serve as crucial hubs for ...