The EMBO Journal2d
New players and targets in mannose 6-phosphate-dependent lysosomal sorting
Amidst the wide variety of glycan modifications that are carried out in the Golgi apparatus, the addition of mannose 6-phosphate (M6P) to the N-linked glycans of lysosome-resident hydrolase enzymes ...
The EMBO Journal8h
The N-terminal region of DNMT3A engages the nucleosome surface to aid chromatin recruitment
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. DNA methyltransferase 3A (DNMT3A) plays a ...
The EMBO Journal5d
Interleukin-2-mediated NF-κB-dependent mRNA splicing modulates interferon gamma protein production
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. IL-2 stimulation post-transcriptionally ...
The EMBO Journal2d
Melanin-like nanoparticles slow cyst growth in ADPKD by dual inhibition of oxidative stress and CREB
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Melanin-like nanoparticles (MNPs) have ...
The EMBO Journal5d
STING induces HOIP-mediated synthesis of M1 ubiquitin chains to stimulate NF-κB signaling
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. STING activation by cyclic dinucleotides ...
The EMBO Journal5d
PTGS is dispensable for the initiation of epigenetic silencing of an active transposon in Arabidopsis
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. PTGS facilitates but is not required for the ...
The EMBO Journal5d
The DNA demethylase TET1 modifies the impact of maternal folic acid status on embryonic brain development
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Interactions between modified maternal folic ...
The EMBO Journal5d
Structural insight into Okazaki fragment maturation mediated by PCNA-bound FEN1 and RNaseH2
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. PCNA is a master coordinator of many ...
The EMBO Journal6d
Nuclear receptor E75/NR1D2 promotes tumor malignant transformation by integrating Hippo and Notch pathways
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Hormone therapy resistance and the ensuing ...
The EMBO Journal5d
The role of PM2.5 exposure in lung cancer: mechanisms, genetic factors, and clinical implications
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Lung cancer is one of the most critical global ...
The EMBO Journal5d
Fibrillarin homologs regulate translation in divergent cell lineages during planarian homeostasis and regeneration
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. fbl-1 and fbl-2 are required for planarian ...