We read with great interest the article of Ratziu and colleagues, who evaluated the potential of thrombospondin-2 (TSP2), insulin-like growth factor binding protein 7, CD163 and growth differentiation ...

Background Depending on the colorectal cancer (CRC) screening programme, a colonoscopy should be performed within 1–3 months ...

Background Postdischarge morbidity and mortality is high in acute pancreatitis (AP) and pathophysiological mechanisms remain ...

Background The prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) is rapidly increasing with high ...

Background Chronic stress is a known risk factor for cancer metastasis. However, the underlying mechanisms, particularly ...

1 Pancreatic Research Group, Department of Gastroenterology, Bankstown-Lidcombe and Liverpool Hospitals, and University of New South Wales, Sydney, Australia 2 Pancreatic Research Group, University of ...

1 Nerve-Gut Research Laboratory, Discipline of Medicine, Faculty of Health Sciences, The University of Adelaide and Department of Gastroenterology and Hepatology, Royal Adelaide Hospital, Adelaide, ...

2 Zhejiang Provincial Key Laboratory of Pancreatic Disease, Hangzhou, China Background Intrahepatic cholangiocarcinoma (ICC) is a highly aggressive malignancy with limited treatment options and poor ...

1 Institute of Immunology, School of Medicine, Zhejiang University, Hangzhou 310058, P.R.China 2 Department of Clinical Laboratory, The Second Affiliated Hospital, School of Medicine, Zhejiang ...

The aim of this study was to establish the relative importance of risk factors for mortality after acute upper gastrointestinal haemorrhage, and to formulate a simple numerical scoring system that ...

Background Diffuse gastric cancer (DGC) is the most common manifestation in germline CTNNA1 variant carriers, with one study estimating a 49–57% lifetime risk by age 80. Knowledge on CTNNA1-associated ...

Objective In the tumour microenvironment, critical drivers of immune escape include the oncogenic activity of the tumour cell-intrinsic osteopontin (OPN), the expression of programmed death ligand 1 ...