In a recent address, San Francisco 49ers head coach Kyle Shanahan stepped up to defend rookie wide receiver Jacob Cowing ...

Just two games into the season, the Rams (0-2) are approaching desperate times as they prepare to face the San Francisco ...

By creating a numbers advantage in the stands, 49ers fans allow quarterback Brock Purdy and the rest of San Francisco's ...

Vikings star wide receiver Justin Jefferson was forced out of the game late in the third quarter against San Francisco with a ...

The absence of star players presents a significant challenge, but the 49ers' collective resolve remains strong. In recent ...

Brophy Prep football travels to Perry for a road game, with the winner having a much clearer road to the Open Division playoffs in November.

The Los Angeles Rams host the San Francisco 49ers on Sunday as both NFC West rivals try to shake off dismal Week 2 ...

San Francisco 49ers quarterback Brock Purdy isn't letting early-season injuries shake his confidence. Although he has been ...

Injuries have caused many problems for the San Francisco 49ers this year, and now Brock Purdy has lost another offensive weapon, in addition to Christian McCaffrey and Deebo Samuel. It has been a ...

Although the Rams-49ers rivalry has been decidedly tilted in San Francisco's direction in recent years, the games have still been must-see spectacles.

For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub. The 229 passing yards the Rams allow per game makes them the NFL’s 24th-ranked pass defense this season.