The San Francisco 49ers on Tuesday announced how they’d replace running back Christian McCaffrey. In a slew of roster moves ...

49ers head coach Kyle Shanahan told reporters Monday that McCaffrey suffered a posterior cruciate ligament (PCL) injury ...

Let's take a look back at how the previous Madden cover stars have fared to see if the 49ers star RB has anything to fear ...

The San Francisco 49ers aren't in the position they want to be right now and it seems like this just isn't their year.

The 49ers placed McCaffrey (knee) on injured reserve Tuesday.

Rookie fourth-round pick Isaac Guerendo seemed to be an afterthought in the San Francisco 49ers backfield with Christian ...

The San Francisco 49ers and fantasy football players who were relying on the NFC West team's running backs are probably all ...

RB Christian McCaffrey suffers potentially season-ending knee injury in loss to Bills, adding to team's struggles.

Christian McCaffrey may have suffered an isolated PCL tear against the Buffalo Bills, a rare injury that could end his season ...

NFL season appears to be over for Christian McCaffrey, which is why the San Francisco 49ers have added two new running backs ...

Ex-New York Jets running back Israel Abanikanda landed on his feet signing with the San Francisco 49ers to help replace ...

The San Francisco 49ers have officially placed running back Christian McCaffrey on injured reserve. He sustained a PCL injury ...