Gut

Oncological impact of universal endoscopic submucosal dissection for large Barrett’s cancers

Background Oncological principles favour en bloc R0 excision for curative endoscopic resection. In Barrett’s neoplasia, ...
Gut

LY6D identifies persistent stem-like cells driving pancreatic tumourigenesis

Background Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy characterised by remarkable cellular ...
Gut

Zinc-dependent RNA-binding protein controls hepatocyte senescence and recovery from alcohol-related liver failure

Background Why alcohol-associated liver disease (ALD) resolves after abstinence in most people but progresses to liver ...
Gut

Role of A2 beta casein in milk-induced eosinophilic oesophagitis: novel in-vivo and in-vitro findings

We read with interest the article by Santacroce about personalised medicine in eosinophilic oesophagitis (EoE) and the ...
gut.bmj

CNNM4: a ferroptotic vulnerability in cholangiocarcinoma

Cholangiocarcinoma (CCA) represents one of the most aggressive malignancies affecting the biliary tree, with limited treatment options and high mortality rates. Despite recent advances in molecular ...
gut.bmj

Treatment of non-constipated irritable bowel syndrome with the histamine 1 receptor antagonist ebastine: a randomised, double-blind, placebo-controlled trial

Correspondence to Professor Guy Boeckxstaens, Department of Chronic Diseases, Metabolism, and Ageing, KU Leuven, Leuven, Belgium; guy.boeckxstaens{at}kuleuven.be Objective We evaluated the histamine 1 ...
gut.bmj

Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study

Background and aims: Melatonin, a sleep promoting agent, is involved in the regulation of gastrointestinal motility and sensation. We aimed to determine if melatonin was effective in improving bowel ...
gut.bmj

The Asia-Pacific Colorectal Screening score: a validated tool that stratifies risk for colorectal advanced neoplasia in asymptomatic Asian subjects

1 Department of Medicine, National University of Singapore, Singapore, Singapore 2 Department of Internal Medicine, National Taiwan University, Taipei, Taiwan 3 Department of Medicine and Therapeutics ...
gut.bmj

Gut, inflammation and osteoporosis: basic and clinical concepts

1 Christian Doppler Research Laboratory for Gut Inflammation and Department of Medicine, Division of Gastroenterology and Hepatology, Medical University Innsbruck, Austria 2 Department of Medicine “T” ...
gut.bmj

A reproducible grading scale for histological assessment of inflammation in ulcerative colitis

Dr K Geboes, Department of Pathology, University Hospital, KULeuven, Minderbroedersstraat 12, 3000 Leuven, Belgium. Email: Karel.Geboes{at}uz.kuleuven.ac.be BACKGROUND Evaluation of histological ...
gut.bmj

Diffusion-weighted magnetic resonance without bowel preparation for detecting colonic inflammation in inflammatory bowel disease

1 Inserm, U954 and Department of Hepato-Gastroenterology, University Hospital of Nancy, Vandoeuvre-lès-Nancy, France 2 Departement of Radiology, University Hospital of Nancy, Vandoeuvre-lès-Nancy, ...
gut.bmj

Golgi protein 73 (GOLPH2) is a valuable serum marker for hepatocellular carcinoma

1 Department of Liver Surgery, Peking Union Medical College (PUMC) Hospital, PUMC, Chinese Academy of Medical Sciences, Beijing, China 2 Cancer Institute and Hospital, PUMC, Chinese Academy of Medical ...