Dexmedetomidine (Dexased, Dexdomitor, Dexmedesed, Sileo) is a medicine that’s FDA-approved for dogs and cats as a sedative. Your veterinarian can give it to help calm your pet before a minor ...

In a multicenter, double-blind trial, we randomly assigned mechanically ventilated adults with sepsis to receive dexmedetomidine (0.2 to 1.5 μg per kilogram of body weight per hour) or propofol ...

Dexmedetomidine infusion at 1 μg/kg/hr during the procedure and at 0.5 μg/kg/hr for 2 hrs after the procedure: Effective sedation during cardiac catheterization: Rozmiarek et al 27: ...

The Food and Drug Administration (FDA) has granted Breakthrough Therapy designation to BXCL501 (dexmedetomidine; BioXcel Therapeutics) for the acute treatment of agitation associated with dementia.

SAN FRANCISCO — Time to successful extubation in mechanically ventilated ICU patients did not significantly differ when comparing dexmedetomidine vs. propofol and clonidine vs. propofol ...

Drugs such as dexmedetomidine that bind to the norepinephrine alpha-2a (α 2a) adrenergic receptor are effective analgesics, but their sedative effects limit their widespread use.

Dexmedetomidine produces sedation while maintaining a degree of arousability and may reduce the duration of mechanical ventilation and delirium among patients in the intensive care unit (ICU). The ...

Dexmedetomidine administration early in the postpartum period was associated with significantly lower positive postpartum depression incidence compared with placebo, researchers reported in JAMA ...

Cite this: A Cost-Minimization Analysis of Dexmedetomidine Compared With Midazolam For Long-Term Sedation In The Intensive Care Unit. F1000: "Changes Clinical Practice" - Medscape - Apr 05, 2010.

For the study, researchers randomly assigned patients to receive dexmedetomidine, a sedative, or a saline placebo infusion during surgery and for two hours while in recovery. They assessed ...