The combination of preoperative opioid use and depression increased postsurgical risk for chronic postsurgical pain and persistent opioid use.

Opioids may cause short-term improvement in mood, but long-term use imposes risk of new-onset depression, a Saint Louis University study shows. The study, "Prescription Opioid Duration, Dose, and ...

Chronic opioid therapy is often misunderstood as primarily producing euphoria, even in long-term pain patients. In reality, ...

An analysis of National Survey on Drug Use and Health (NSDUH) data showed that individuals with opioid use disorder have 1.88 ...

Is there a safe opioid? Scientists discovered DFNZ, a high-potency nitazene that relieves pain without the risk of overdose ...

A nurse fills a syringe of the Johnson & Johnson single dose vaccine during a walk-up clinic on May 6, 2021, in D.C. (Amanda Voisard/For The Washington Post) Lee Hockstader’s May 22 online column, ...

Ingesting just one oxycodone tablet and moderately consuming alcohol can increase the risk of respiratory depression, a potentially fatal side effect caused by drug overdose, according to a new study ...

A novel mu-opioid receptor agonist showed strong analgesia without respiratory depression, tolerance, or significant ...

More good news in the battle against opioid addiction. Scientists have reopened research into a class of opioids that were ...

Last week, researchers dropped a bombshell report on DFNZ, a developing new medicine derived from a class of drugs once ...