With only a few weeks left on the college football slate, NFL draft season is beginning to hit its stride. Before the San Francisco 49ers meet the Buffalo Bills in Week 13, USA TODAY’s NFL Draft Wire released their latest predictions for the 2025 draft with a new mock draft.

Kyle Shanahan and the San Francisco 49ers are having a nightmare in the 2024 season. It has been confirmed that another star player is seriously injured. Kyle Shanahan and the San Francisco 49ers were favorites to win the Super Bowl before the start of the 2024 season.

The San Francisco 49ers are 5-6 entering their matchup with the Buffalo Bills on Sunday, and an NFL executive called out 49ers HC Kyle Shanahan for mishandling late-game situations. Colin Cowherd discusses this criticism and if it’s the biggest issue the 49ers have right now.

We thought San Francisco was poised for a massive second-half run after the Week 9 bye with Christian McCaffrey back, but the 49ers haven't looked good over their last three contests.  It wasn't a surprise the 49ers fell to the Green Bay Packers on Sunday with so many key contributors out.

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Bills' QB Josh Allen is the current favorite for MVP. Expectations aren't something I like to make a habit. However, it's hard not to expect the best from Allen and the Bills this week. Beating the Chiefs the way they did helped them check off that confidence box, and they did it on their 12th straight week of football.

Quarterback is arguably the most important position in all of sports. Having the right player under center is extremely important, as it could be the difference between an NFL team contending for a Super Bowl and missing the playoffs altogether.

The Los Angeles Rams not the only team in their division to be playing a non-divisional road game this week. In fact, all four teams in the NFC West will be tra

Christen Harper Goff, Alix Earle, Sarah Jane Ramos and more NFL WAGs share with PEOPLE exclusively how they creatively plan to enjoy Thanksgiving on game day

Former Buffalo Bills defensive end Leonard Floyd spoke about facing his old team on Sunday night with the San Francisco 49ers.