How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But ...

These sequences are extremely prone to mutations and rank among the most functionally important regions in the entire human ...

Researchers have revealed a new mechanism underlying how spatial distance between specific regions of DNA is linked to bursts of gene activity. Using advanced cell imaging techniques and computer ...

Philadelphia, April 17, 2025 – Researchers from Children’s Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania (Penn Medicine) have successfully ...

A new study suggests that mutations in regions of the genome that help control gene activity may influence the development of autism. When you purchase through links on our site, we may earn an ...

The study shows that a long non-coding RNA called CISTR-ACT acts as a master regulator of cell size, influencing how large or ...

The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark ...

In the early 1980s, David Gilmour, now an emeritus biochemistry and molecular biology professor at Pennsylvania State University, joined the laboratory of geneticist and biochemist John Lis as a ...

DNA contains foundational information needed to sustain life. Understanding how this information is stored and organized has been one of the greatest scientific challenges of the last century. With ...

Originally classified as ‘junk DNA’, genomic regions which are transcribed into RNAs that do not serve as template for protein production have attracted increasing attention in the last two decades.