Complement component 3, often called C3, is an essential protein of the immune system. This protein plays a vital role in the body’s innate immune system, providing: the first line of defense against ...

Global understanding of complement has shifted and developed since the 21st century: from our idea of a blood-based antibiotic system to a global regulator of immunity and tissue homeostasis. Recent ...

Astrocytes have been implicated in Alzheimer’s and other neurodegenerative diseases, but these beautiful, star-shaped cells are notoriously difficult to study. Animal models are little help, because ...