The defense. The Titans lost a trio of safeties to injuries after a couple of series. They also allowed seven straight third-down conversions. Tennessee gave up points on the 49ers' first five possessions — four of them touchdowns. The Titans didn't force a single punt.

The Tennessee Titans are struggling, and many fans have turned their attention to the 2026 NFL draft and the potential draft order.

NASHVILLE, Tenn. (WSMV) - When the Tennessee Titans face the Kansas City Chiefs on December 21st, Patrick Mahomes will not be on the field.

Tennessee Titans star defensive tackle Jeffery Simmons returned from San Francisco and discovered his home had been broken into during the road trip.

The Chiefs-Titans game will be on CBS (KCTV 5 in Kansas City). In Wichita, it’s on KWCH (Channel 12). The game will also be broadcast on radio via KFNZ (96.5 FM) in the KC area and KNSS (98.7 FM) in the Wichita area. Despite losing Mahomes, the Chiefs are a 3 1/2-point favorite with the over/under set at 37 1/2.

Listed as inactive for the 49ers were wide receiver Jordan Watkins, running back Jordan James, linebacker Nick Martin, linebacker Tatum Bethune, defensive lineman Sebastian Valdez, defensive lineman Sam Okuayinonu and defensive lineman Jordan Elliott. Elliott was a late addition ot the injury report with a knee issue.

Our experts' predictions are in for Tennessee Titans vs. San Francisco 49ers on Sunday. Here's who our experts are picking to win the Week 15 NFL game.

Metro Police are investigating a burglary at the home of Tennessee Titans player Jeffery Simmons who was away with the team this weekend as they took on San Francisco.

Ricky Pearsall is facing another injury setback. He had six catches for 96 yards on Sunday, helping the San Francisco 49ers beat the Tennessee Titans 37-24.