The redshirt freshman’s left ankle was caught at an awkward angle beneath Louisville defensive end Ashton Gillotte’s hip on a twisting tackle for a 4-yard loss at midfield.

Pitt quarterback Eli Holstein will return from injury to start Saturday against Louisville, according to multiple reports. Holstein left two games within the past month with apparent head injuries. He departed the Panthers' 41-13 win over Syracuse on Oct.

Pittsburgh quarterback Eli Holstein was carted off the field with a left leg injury sustained while being sacked in the first quarter of Saturday's Atlantic Coast Conference game at Louisville.The redshirt freshman's left ankle was caught at an awkward angle beneath Louisville defensive end Ashton Gillotte's hip on a twisting tackle for a 4-yard loss at midfield.